Alsace is the fourth-smallest of the 26 regions of France in land area (8,280 km²), and the smallest in metropolitan France. It is also the sixth-most densely populated region in France (third most densely populated region in metropolitan France), with 222 inhabitants per km² (total population in January 2008: 1,836,000). Alsace is located on France's eastern border and on the west bank of the upper Rhine adjacent to Germany and Switzerland. The political, economic and cultural capital as well as largest city of Alsace is Strasbourg. That town being the seat of dozens of international organizations and bodies, Alsace is politically one of the most important regions in the European Union.